California Reports First Known U.S. Case of Emerging Mpox Strain

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What You Need to Know: CDPH has reported to the Centers for Disease Control and Prevention (CDC) the first case of clade I mpox in the United States. Clade I is different than clade II, the strain of mpox that has been circulating in California and the United States since 2022. The individual is isolating at home and the risk to the public remains very low.

SACRAMENTO – The California Department of Public Health (CDPH) has identified through laboratory testing the first known case of clade I mpox in the United States. This case was confirmed in an individual who recently traveled from Africa and is related to the ongoing outbreak of clade I mpox in Central and Eastern Africa.

Historically, clade I has caused more severe illness than clade II, however, recent infections from clade I mpox may not be as clinically severe as in previous outbreaks, especially when cases have access to quality medical care…

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