SANTA CLARA, Calif. — After missing last week because of a hamstring injury, San Francisco 49ers running back Isaac Guerendo is set to Monday night against the Detroit Lions .
Guerendo, who has been listed as limited in practice this week with foot and hamstring issues, has no injury designation and is set to play on “Monday Night Football.”
After a slew of injuries at running back that has put Christian McCaffrey (knee), Elijah Mitchell (hamstring) and Jordan Mason (ankle) on injured reserve, Guerendo stepped into the starting role against the Chicago Bears on Dec. 8…