Researchers have created a highly detailed cellular map of Alzheimer’s disease progression, revealing new insights into the disease’s development.
By analyzing over 3.4 million cells, scientists identified specific neuron types that are lost early in Alzheimer’s, potentially unlocking new therapeutic targets. Their work shows two disease phases: a slow, early cellular disruption followed by a rapid neuronal decline that coincides with cognitive symptoms.
A team of scientists from the Allen Institute for Brain Science, UW Medicine, and Kaiser Permanente Washington Health Research Institute have created the most detailed picture of how Alzheimer’s disease (AD) progresses at the cellular level to date…